abstract：:The recent discovery of a wide range of henipavirus-like viruses circulating in Megabats in Africa raises the question as to the zoonotic potential of these pathogens given the high human mortality rates seen with their pathogenic relatives Nipah virus and Hendra virus. In the absence of cultured infectious African He...

journal_title：Virus research

authors： Lawrence P,Escudero Pérez B,Drexler JF,Corman VM,Müller MA,Drosten C,Volchkov V

更新日期：2014-03-06 00:00:00

abstract：:Baculoviruses are a promising gene delivery vector. They have the ability to express large transgenes in mammalian cells without displaying pathogenicity in humans; however, little is known about their transduction mechanisms in target cells. In this study, we use colocalization and live-cell imaging studies to elucid...

journal_title：Virus research

authors： Liu Y,Joo KI,Lei Y,Wang P

更新日期：2014-03-06 00:00:00

abstract：:Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV). All PPVs are known to be zoonotic, leading to cir...

journal_title：Virus research

authors： Friederichs S,Krebs S,Blum H,Wolf E,Lang H,von Buttlar H,Büttner M

更新日期：2014-03-06 00:00:00

abstract：:Experimental infection studies with bluetongue virus (BTV) in the mammalian host have a history that stretches back to the late 18th century. Studies in a wide range of ruminant and camelid species as well as mice have been instrumental in understanding BTV transmission, bluetongue (BT) pathogenicity/pathogenesis, vir...

journal_title：Virus research

authors： Coetzee P,van Vuuren M,Venter EH,Stokstad M

更新日期：2014-03-01 00:00:00

abstract：:Canine distemper virus (CDV) is a major pathogen of dogs and represents a serious threat to both unvaccinated and vaccinated animals. This study surveyed dogs with or without clinical signs related to canine distemper from different regions of Brazil from 2008 to 2012. A total of 155 out of 386 animals were found to b...

journal_title：Virus research

authors： Budaszewski Rda F,Pinto LD,Weber MN,Caldart ET,Alves CD,Martella V,Ikuta N,Lunge VR,Canal CW

更新日期：2014-02-13 00:00:00

abstract：:Major progress in Dengue virus (DENV) biology has resulted from the use of infectious clones obtained through reverse genetics. The construction of these clones is commonly based on high- or low-copy number plasmids, yeast artificial chromosomes, yeast-Escherichia coli shuttle vectors, and bacterial artificial chromos...

journal_title：Virus research

authors： Usme-Ciro JA,Lopera JA,Enjuanes L,Almazán F,Gallego-Gomez JC

更新日期：2014-02-13 00:00:00

abstract：:The E2 glycoprotein of classical swine fever virus (CSFV) is involved in viral infection and induction of neutralizing antibodies. Little is known about how E2 interacts with host cells. To understand the cellular factors involved in viral replication cycle, E2 was used as bait in yeast two-hybrid screens, resulting i...

journal_title：Virus research

authors： He F,Ling L,Liao Y,Li S,Han W,Zhao B,Sun Y,Qiu HJ

更新日期：2014-01-22 00:00:00

abstract：:Blackberry yellow vein disease is the most important viral disease of blackberry in the United States. Experiments were conducted to characterize a new virus identified in symptomatic plants. Molecular analysis revealed a genome organization resembling Grapevine leafroll-associated virus 3, the type species of the gen...

journal_title：Virus research

authors： Thekke-Veetil T,Aboughanem-Sabanadzovic N,Keller KE,Martin RR,Sabanadzovic S,Tzanetakis IE

更新日期：2013-12-26 00:00:00

abstract：:In recent years, the spread of Duck Hepatitis A Viruses (DHAVs) has represented a serious threat and significant economic impact in duck industry of China. The sixteen reported DHAV isolates (15 DHAV-1 strains and one DHAV-3) were identified from infected ducks with clinical symptoms in China between 2009 and 2012. In...

journal_title：Virus research

authors： Li J,Bi Y,Chen C,Yang L,Ding C,Liu W

更新日期：2013-12-26 00:00:00

abstract：:Reports of human infections with highly pathogenic H5N1 avian influenza viruses in many countries in Asia and Africa with varying case fatality rates highlight the pandemic potential of these viruses. In order to contain a rapidly spreading influenza virus in a pandemic scenario, a vaccine which can induce rapid and r...

journal_title：Virus research

authors： Vemula SV,Amen O,Katz JM,Donis R,Sambhara S,Mittal SK

更新日期：2013-12-26 00:00:00

abstract：:Tick-borne encephalitis (TBE) is a serious human neurological disease caused by TBE virus (TBEV). However, the mechanisms of TBEV-caused pathogenesis remain unclear. The endoplasmic reticulum (ER) stress response, also defined as the unfolded protein response (UPR), is an important conserved molecular signaling pathwa...

journal_title：Virus research

authors： Yu C,Achazi K,Niedrig M

更新日期：2013-12-26 00:00:00

abstract：:Viral expression varies widely between untransformed HTLV-1 positive clones derived from infected individuals without malignancy. Here we show that, in the absence of malignancy, 68% of HTLV-1 positive clones carry deleted (10%) or methylated (58%) 5' LTR. These changes were found to contribute to the fluctuation of v...

journal_title：Virus research

authors： Sibon D,Zane L,Idrissi ME,Delfau-Larue MH,Gessain A,Gout O,Mortreux F,Wattel E

更新日期：2013-12-26 00:00:00

abstract：:Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans and cause severe respiratory disease and fatalities. Currently, these viruses are not efficiently transmitted from person to person, although limited human-to-human transmission may have occurred. Nevertheless, further adaptation of avian H5N1...

journal_title：Virus research

authors： Imai M,Herfst S,Sorrell EM,Schrauwen EJ,Linster M,De Graaf M,Fouchier RA,Kawaoka Y

更新日期：2013-12-05 00:00:00

abstract：:Highly pathogenic H5N1 influenza viruses have been isolated from a number of avian and mammalian species. Despite intensive control measures the number of human and animal cases continues to increase. A more complete understanding of susceptible species and of contributing environmental and molecular factors is crucia...

journal_title：Virus research

authors： Kaplan BS,Webby RJ

更新日期：2013-12-05 00:00:00

abstract：:The immunopathogenesis of severe hand, foot and mouth disease (HFMD) remains elusive. This study revealed that enterovirus 71 (EV71) epitope-specific CD4+ T cell responses of HFMD patients were skewed toward a Th2 cytokine profile. Patients that demonstrated higher levels of IL-4 expression in their CD4 T cells follow...

journal_title：Virus research

authors： Wei R,Xu L,Zhang N,Zhu K,Yang J,Yang C,Deng C,Zhu Z,De Groot AS,Altmeyer R,Zeng M,Leng Q

更新日期：2013-10-01 00:00:00

abstract：:Infectious salmon anaemia virus (ISAV) is an orthomyxovirus causing anaemia and circulatory disease with high mortality in farmed Atlantic salmon (Salmo salar). Orthomyxoviruses are unusual as RNA viruses as they replicate in the nucleus and some viral transcripts undergo splicing. The nuclear replication necessitates...

journal_title：Virus research

authors： Ramly RB,Olsen CM,Braaen S,Rimstad E

更新日期：2013-10-01 00:00:00

abstract：:Enterovirus 71 (EV71) is a single-stranded RNA virus that belongs to Picornaviridae family. It causes the hand-foot-and-mouth disease and fatal neurological diseases in young children and infants. The mechanism of EV71 pathogenesis remains obscure. The intestinal tract is the initial site of EV71 replication, but no o...

journal_title：Virus research

authors： Chi C,Sun Q,Wang S,Zhang Z,Li X,Cardona CJ,Jin Y,Xing Z

更新日期：2013-09-01 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) in humans is caused mainly by Enterovirus 71(EV71) and Coxsackievirus A16 (CVA16). EV71 is associated with severe HFMD cases but not CVA16. Use of IgM-capture enzyme-linked immunosorbent assay (ELISA) is important for the early diagnosis of EV71 infection, but cross-reactivity of th...

journal_title：Virus research

authors： Wang C,You A,Tian X,Zhao M,Chen Y,Lin T,Zheng J,Xiao M,Zhang Y,Kuang L,Zhou Z,Zhu B

更新日期：2013-09-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus. VSV's broad cell tropism makes it a popular model virus for many basic research applications. In addition, a lack of preexisting human immunity against VSV, inherent oncotropism and other features make VSV a widely used platform f...

journal_title：Virus research

authors： Hastie E,Cataldi M,Marriott I,Grdzelishvili VZ

更新日期：2013-09-01 00:00:00

abstract：:A previously unknown iflavirus has been identified in a laboratory colony of the brown planthopper, Nilaparvata lugens. The iflavirus-like sequence was first identified in contig sequences obtained from transcriptome sequencing (RNA-seq) of the brown planthopper. The complete viral genome was resequenced using the San...

journal_title：Virus research

authors： Murakami R,Suetsugu Y,Kobayashi T,Nakashima N

更新日期：2013-09-01 00:00:00

abstract：:Circulifer tenellus virus 1 (CiTV1) is the prototypical example of an unusual group of dsRNA viruses associated with insects and for which ecological data are lacking. A San Joaquin Valley (SJV), California population of the beet leafhopper (BLH; Circulifer tenellus [Baker]) was sampled for CiTV1 in 2010. Among 365 BL...

journal_title：Virus research

authors： Spear A,Yokomi R,French R,Stenger DC

更新日期：2013-09-01 00:00:00

abstract：:p29, a newly identified Kaposi's sarcoma-associated herpesvirus (KSHV) protein, is the product of ORF67, the positional homolog of the conserved herpesvirus protein UL34. Like its homologues in other herpesviruses, p29 is expressed early during viral lytic cycle, and is localized on the nuclear rim. Upon chemical indu...

journal_title：Virus research

authors： Farina A,Santarelli R,Bloise R,Gonnella R,Granato M,Bei R,Modesti A,Cirone M,Bengtsson L,Angeloni A,Faggioni A

更新日期：2013-08-01 00:00:00

abstract：:Genetic factors are presumed to influence the incidence of feline infectious peritonitis (FIP), especially among pedigreed cats. However, proof for the existence of such factors has been limited and mainly anecdotal. Therefore, we sought evidence for genetic susceptibility to FIP using feline high density single nucle...

journal_title：Virus research

authors： Golovko L,Lyons LA,Liu H,Sørensen A,Wehnert S,Pedersen NC

更新日期：2013-07-01 00:00:00

abstract：:The Foot-and-mouth disease virus (FMDV) causes important economical losses in livestock farming. In order to develop a novel subunit vaccine against FMDV, we constructed recombinant baculoviruses that display the protein VP1 of FMDV on their surface, with either polar (fused to gp64) or nonpolar (fused to anchor membr...

journal_title：Virus research

authors： Peralta A,Maroniche GA,Alfonso V,Molinari P,Taboga O

更新日期：2013-07-01 00:00:00

abstract：:Okra leaf curl disease (OLCD) is the most important viral disease of okra in West Africa. In this study, a complex of begomoviruses and associated DNA satellites were identified in symptomatic okra plants from southwestern Cameroon. Sequence analyses showed that two of the plants (Lik1 and Njo5) were infected with a b...

journal_title：Virus research

authors： Leke WN,Sattar MN,Ngane EB,Ngeve JM,Kvarnheden A,Brown JK

更新日期：2013-06-01 00:00:00

abstract：:Swine influenza virus (SIV) is not only an important respiratory pathogen in pigs but also a threat to human health. The pandemic influenza A(H1N1)pdm09 virus likely originated in swine through reassortment between a North American triple reassortant and Eurasian avian-like SIV. The North American triple reassortant v...

journal_title：Virus research

authors： Said A,Lange E,Beer M,Damiani A,Osterrieder N

更新日期：2013-05-01 00:00:00

abstract：:Influenza virus rgVac1sub-P0 (H5N1) (rgVac1-P0), in which a pair of dibasic amino acid residues was introduced at the cleavage site of the HA of a reassortant of H5N2 and H7N1 viruses of duck origin, was low pathogenic in chickens. Vac1sub-P3 (H5N1) (Vac1-P3) was selected as a highly pathogenic avian influenza virus b...

journal_title：Virus research

authors： Yamamoto N,Soda K,Sakoda Y,Okamatsu M,Kida H

更新日期：2013-05-01 00:00:00

abstract：:Hepatitis D virus (HDV) is the smallest animal infecting RNA virus with unique features distinguishing it from other Hepatitis viruses. Codon usage variation is considered as an indicator of the forces shaping genome evolution. RSCU (relative synonymous codon usage) values, nucleotide contents, ENC (effective number o...

journal_title：Virus research

authors： Bishal AK,Mukherjee R,Chakraborty C

更新日期：2013-05-01 00:00:00

abstract：:African swine fever (ASF) is a viral hemorrhagic disease with different clinical and lesional changes depending of virulence of strains/isolates and immunological status of pigs. In acute and subacute forms of ASF, severe vascular changes are present, with hemorrhages in different organs (mainly melena, epistaxis, ery...

journal_title：Virus research

authors： Gómez-Villamandos JC,Bautista MJ,Sánchez-Cordón PJ,Carrasco L

更新日期：2013-04-01 00:00:00

abstract：:Almost all viruses can be neutralized by antibodies. However, there is some controversy about antibody-mediated neutralization of African swine fever virus (ASFV) with sera from convalescent pigs and about the protective relevance of antibodies in experimentally vaccinated pigs. At present, there is no vaccine availab...

journal_title：Virus research

authors： Escribano JM,Galindo I,Alonso C

更新日期：2013-04-01 00:00:00

abstract：:An insect High-Five cell line was generated constitutively and stably expressing the VP2 protein of rotavirus RF strain leading to the formation of core-like particles. The integration of the VP2 gene was confirmed by PCR, Real-time PCR and Southern blot, and the protein expression was confirmed by Western blot and im...

journal_title：Virus research

authors： Shoja Z,Tagliamonte M,Jalilvand S,Mokhtari-Azad T,Hamkar R,Shahmahmoodi S,Rezaei F,Tornesello M,Buonaguro FM,Buonaguro L,Nategh R

更新日期：2013-03-01 00:00:00

abstract：:Retroviruses and retrotransposons package genomic RNA into virus-like particles (VLPs) in a poorly understood process. Expression of the budding yeast retrotransposon Ty3 results in the formation of cytoplasmic Ty3 VLP assembly foci comprised of Ty3 RNA and proteins, and cellular factors associated with RNA processing...

journal_title：Virus research

authors： Clemens K,Bilanchone V,Beliakova-Bethell N,Larsen LS,Nguyen K,Sandmeyer S

更新日期：2013-02-01 00:00:00

abstract：:Four species of Diuris temperate terrestrial orchids from wild and captive populations were tested for the presence of polyadenylated RNA viruses. The genomes of three exotic viruses were determined: two potyviruses, Bean yellow mosaic virus and Ornithogalum mosaic virus, and the polerovirus Turnip yellows virus. The ...

journal_title：Virus research

authors： Wylie SJ,Li H,Dixon KW,Richards H,Jones MG

更新日期：2013-01-01 00:00:00

abstract：:The first influenza pandemic of this century was declared in April of 2009, with the emergence of a novel H1N1 influenza A virus strain (H1N1pdm). Understanding the evolution of H1N1pdm populations within the South American region is essential for studying global diversification, emergence, resistance and vaccine effi...

journal_title：Virus research

authors： Goñi N,Moratorio G,Coppola L,Ramas V,Comas V,Soñora M,Chiparelli H,Cristina J

更新日期：2012-12-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is an RNA virus and eight clades of HDV have been identified. HDV clade 3 (HDV-3) is isolated only in the northern area of South America. The outcome of HDV-3 infection is associated with severe fulminant hepatitis. Variations in the large delta antigen (LDAg) between HDV clade 1 (HDV-1) an...

journal_title：Virus research

authors： Huang CR,Wang RY,Hsu SC,Lo SJ

更新日期：2012-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a modern-day pandemic; 2-3% of the world's population are thought to be infected with the virus and are subsequently at risk of developing end-stage liver diseases. The traditional standard of care (SOC) for HCV-infected patients has been limited to a regimen of pegylated-interferon alpha (p...

journal_title：Virus research

authors： Belda O,Targett-Adams P

更新日期：2012-12-01 00:00:00

abstract：:Citrus psorosis (CPsV) and Mirafiori lettuce big-vein virus (MiLBVV) belong to the family Ophioviridae, plant viruses with filamentous nucleocapsids and segmented genomes of negative polarity, causing the worldwide distributed citrus psorosis and lettuce big-vein diseases, respectively. To gain insight into the replic...

journal_title：Virus research

authors： Peña EJ,Robles Luna G,Zanek MC,Borniego MB,Reyes CA,Heinlein M,García ML

更新日期：2012-12-01 00:00:00

abstract：:We have previously described the efficient homologous recombination system between 5' subgenomic RNA3a (sgRNA3a) and genomic RNA3 of Brome mosaic virus (BMV) in barley protoplasts (Sztuba-Solińska et al., 2011a). Here, we demonstrated that sequence alterations in the coat protein (CP)-binding cis-acting RNA motifs, th...

journal_title：Virus research

authors： Sztuba-Solińska J,Fanning SW,Horn JR,Bujarski JJ

更新日期：2012-12-01 00:00:00

abstract：:Following viral infection, the host responds by mounting a robust anti-viral response with the aim of creating an unfavorable environment for viral replication. As a countermeasure, viruses have elaborated mechanisms to subvert the host response in order to maintain viral protein synthesis and production. In the last ...

journal_title：Virus research

authors： Valiente-Echeverría F,Melnychuk L,Mouland AJ

更新日期：2012-11-01 00:00:00

abstract：:CVB3 virus tropism and tissue access are modulated by cardiac microvascular endothelial cells (CMVECs) in the context of microvasculature. This study was designed to examine biological behaviors of CMVECs following CVB3 infection and its possible effects on cardiac remodeling. Data demonstrated that CVB3 increased cas...

journal_title：Virus research

authors： Xie Y,Liao J,Li M,Wang X,Yang Y,Ge J,Chen R,Chen H

更新日期：2012-10-01 00:00:00